New Method for Predicting Congenital CMV Infection During the Prenatal Period

Tanimura, K. et al. (2016) Clinical Infectious Diseases. DOI:10.1093/cid/ciw707

Image source: Pete Jeffs – Wellcome Images // CC BY-NC-ND 4.0

Image shows illustration of a human cytomegalovirus (HCMV) virus particle

Background: The aim of this prospective study was to determine maternal clinical, laboratory, and ultrasound findings that effectively predict the occurrence of congenital cytomegalovirus (CMV) infection in high-risk pregnant women.

Conclusions: This is the first prospective cohort study to suggest that the presence of CMV-DNA in the maternal uterine cervical secretion and ultrasound fetal abnormalities was predictive of the occurrence of congenital CMV infection in high-risk pregnant women.

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