This study examined whether a multi-method approach to reduce Clostridium difficile infection might be worthwhile at US hospitals. The intervention included antimicrobial stewardship, contact precautions and enhanced environmental cleaning. Data were analysed using a computer model with a five-year time horizon. The focus was people aged 65 years or more whose care was funded by the government. If this programme was implemented nationally, it was estimated that cost savings across all admissions would be US$2.5 billion.
Reference: Slayton RB et al. The cost-benefit of federal investment in preventing clostridium difficile infections through the use of a multifaceted infection control and antimicrobial stewardship program. Infection Control and Hospital Epidemiology. 2015. 36(6): 681 – 687